教育经历

2013.09–2019.12，中南大学生命科学学院，理学博士（硕博连读）

2017.02–2019.02，美国国立卫生研究院，过敏与传染病研究所，博士联合培养

2009.09–2013.06，中南林业科技大学，理学学士

工作经历

2020.04-2022.03，中南大学生命科学学院，博士后

2022.03-至今，中南大学生命科学学院，讲师

研究方向

主要研究方向为运用二代、三代、转录组学测序等基因组学方法解析儿童孤独症非编码RNA变异、结构变异的分子致病机制研究。主持国家自然科学基金青年基金，中国博士后科学基金特别资助，湖南省自然科学基金，湖南省青年科技人才“荷尖”项目,参与国家自然科学基金项目6项，以第一/通讯作者在PNAS、Autism Res等期刊发表研究论文。

代表性论文

[1] Jian Wu*, Lu Xia*, Xiangyu Yao, Xiao Yu, Keyla C. Tumas, Wenxiang Sun, Yang Cheng, Xiao He, Yu-chih Peng, Brajesh K. Singh, Cui Zhang, Chen-Feng Qi, Silvia Bolland, Sonja M. Best, Channe Gowda, Ruili Huang, Timothy G. Myers, Carole A. Long, Rong-Fu Wang^#, and Xin-zhuan Su^#. The E3 ubiquitin ligase MARCH1 regulates antimalaria immunity through interferon signaling and T cell activation. Proc Natl Acad Sci U S A. 2020 Jul 14;117(28):16567-16578. (并列一作)

[2] Shanshan Dong, Qi Tian, Tengfei Zhu, Kangli Wang, Ganting Lei, Yanling Liu, Haofeng Xiong, Lu Shen, Meng Wang, Rongjuan Zhao, Huidan Wu, Bin Li, Qiumeng Zhang, Yujun Yao, Hui Guo, Kun Xia, Lu Xia^#, Zhengmao Hu^#. SLC39A5 dysfunction impairs extracellular matrix synthesis in high myopia pathogenesis. J Cell Mol Med. 2021 Sep; 25 (17):8432-8441. (并列通讯)

[3] Xiao He*, Lu Xia*, Keyla C Tumas,Jian Wu^#,Xin-zhuan Su^#. Type I Interferons And Malaria: A Double-Edge Sword Against A Complex Parasitic Disease, Front. Cell. Infect. Microbiol. 2020 Dec 2;10:594621. (并列一作)

[4] Lu Xia, Jianjun Ou, Kuokuo Li, Hui Guo, Zhengmao Hu, Ting Bai, Jingping Zhao, Kun Xia^#, Fengyu Zhang^#. Genome-wide association analysis of autism identified multiple loci that have been reported as strong signals for neuropsychiatric disorders, Autism Res. 2020 Mar;13(3):382-396.

[5] Lu Xia*, Jian Wu*, Sittiporn Pattaradilokrat, Keyla Tumas, Xiao He, Yu-Chih Peng, Ruili Huang, Timothy G Myers, Carole A Long, Rongfu Wang^#, Xin-Zhuan Su^#. Detection of host pathways universally inhibited after Plasmodium yoelii infection for immune intervention, Sci Rep. 2018 Oct 16;8(1):15280.

[6] Xin-Zhuan Su*^#, Kristin D. Lane, Lu Xia, Juliana M. Sá, Thomas E. Wellems^#. Plasmodium Genomics and Genetics: New Insights into Malaria Pathogenesis, Drug Resistance, Epidemiology, and Evolution, Clin Microbiol Rev. 2019 Jul 31;32(4). pii: e00019-19.

[7] Xiao He, Alison W Ashbrook, Yang Du, Jian Wu, Hans-Heinrich Hoffmann, Cui Zhang, Lu Xia, Yu-Chih Peng, Keyla C Tumas, Brajesh K Singh, Chen-Feng Qi, Timothy G Myers, Carole A Long, Chengyu Liu, Rongfu Wang, Charles M Rice, Xin-Zhuan Su. RTP4 inhibits IFN-I response and enhances experimental cerebral malaria and neuropathology. Proc Natl Acad Sci U S A. 2020 Aug 11;117(32):19465-19474.