研究方向

肾上腺肿瘤与继发性高血压

研究简介

高血压在中国有3.5亿，其中15%是继发性高血压，由肾上腺疾病导致的继发性高血压占10%，照此计算中国继发性高血压有4000万人。重要的是，由肾上腺疾病引起的继发性高血压大部分可以治愈，不要终身服药。但是，这块的筛查与治疗还需要深入与推广。并且，肾上腺肿瘤与遗传密切相关，其中的嗜铬细胞瘤/副神经节瘤部分存在转移，严重影响群众健康。我们湘雅肾上腺肿瘤和继发性高血压研究团队将致力于这项工作，欢迎与我们联系。

学习工作经历

1)2012,10- 中南大学生命科学学院生物化学系，副教授，硕士生导师。

2)2008, 01-2012,09 中南大学生物科学与技术学院生物化学系，讲师。

3)2004,09-2007,12 中南大学医学遗传学国家重点实验室，细胞生物学专业博士研究生学习，导师为张灼华教授，获理学博士学位。

4)2001,09-2004,07 湖南农业大学农学院水稻研究所，作物遗传育种专业硕士研究生学习，导师为陈立云研究员，获农学硕士学位。

5)1996,08-2001,08 湖南省湘潭市农业局种子公司，任助理农艺师、农艺师。

6)1992,09-1996,07 湖南农业大学农学院农学系，农学专业本科学习，获农学学士学位。

科研论文

#:第一作者；*：通讯作者

1)Shuai Gao, Longfei Liu, Zhuolin Li, Yingxian Pang, Jiaqi Shi,Feizhou Zhu*. Seven Novel Genes Related to Cell Proliferation and Migration of VHL-Mutated Pheochromocytoma.Frontiers in Endocrinology, 2021, 12: 598656

2)Yong Peng#, Fei-Zhou Zhu#, Zhi-Xing Chen, Jian-Xiong Zhou, Lu Gan, Shan-Shan Yang, Shuai Gao, Qian-Qian Liu.Characterization of myelin oligodendrocyte glycoprotein (MOG)_35-55specific CD8⁺T cells in Experimental AutoimmuneEncephalomyelitis.Chinese Medical Journal,2019;132(24): 2934-2940.

3)Yalin Liu，Longfei Liu，Feizhou Zhu*.Therapies targeting the signal pathways of pheochromocytoma and paraganglioma. OncoTargets and Therapy, 2019:12, 7227–7241.

4)Peihua Liu#,Feizhou Zhu#, Minghao Li, Daud Athanasius Dube, Qianqian Liu, Cikui Wang, Qiao Xiao, Liang Zhang, Shuai Gao, Zhuolin Li, Bo Zhang, Jing Liu, Longfei Liu, Xiang Chen.Von Hippel-Lindau “Black Forest” mutation inherited in a large Chinese family.Gland Surgery,2019, 8(4):343-353.

5)Hartmut P.H. Neumann,Uliana Tsoy, Vincent Amodru, Martin K. Walz, Irina Bancos,Amit Tirosh,Ravinder Kaur Jeet, Travis McKenzie, Xiaoping Qi, Tushar Bandgar,Sanjeet Kumar Jaiswal, Roman Petrov, Anna Roslyakova, Marina Y. Yukina,Anouk N.A. van der Horst-Schrivers, Annika M.A. Berends, Ana O. Hoff,Luciana Audi Castroneves, Alfonso Massimiliano Ferrara, Silvia Rizzati, Caterina Mian, Sarka Dvorakova, Kornelia Hasse-Lazar, Andrey Kvachenyuk, Mariola Peczkowska, Paola Loli, Feyza Erenler, Stefan Zschiedrich, Tobias Krauss, Madson Q. Almeida, Maria C.B.V. Fragoso, Maria A.A. Pereira, Longfei Liu, Minghao, Feizhou Zhu, Mònica Recasens, Josefina Biarnes Costa, Nelson Wohllk, Eleonora Corssmit, Zulfiya Shafigullina, Jan Calissendorff, Carl Christofer Juhlin, Simona Grozinsky-Glasberg, David Gross, Tada Kunavisarut, Alice H.D. Violante,Tomaz Kocjan,Joanne Ngeow, Uri Yoel, Merav Fraenkel, Ilgin Yildirim Simsir, M. Umit Ugurlu, Athanasia Ziagaki, Camilla Schalin-Jäntti, Luis Robles Díaz, Inna Stepanovna Kudlai, Oliver Gimm, Christina Rebecca Scherbaum, Gadi Abebe-Campino, Giovanni Barbon, Elisa Taschin, Angelica Malinoc, Natalia Valeryevna Khudiakova, Nikita V. Ivanov, Frederic Castinetti, Petr Vlček, Marija Pfeifer, Dmitry Beltsevich, Viacheslav I. Egorov, MD, Stefania Zovato, Ursula Ploeckinger, Özer Makay, Elena Grineva, Francesca Schiavi, Barbara Jarzab, Andrzej Januszewicz, Nalini Shah, Jochen Seufert, Giuseppe Opocher, Thera P. Links, MD, Catharina Larsson, Ronald M. Lechan, Birke Bausch, William F. Young, Charis Eng.Comparison of pheochromocytoma-specific morbidity and mortality among adults with bilateral pheochromocytomas undergoing total adrenalectomy versus cortical-sparing adrenalectomy.JAMA Network Open, 2019 Aug 2;2(8):e198898.

6)Shijing Liao,Yapeng Zhang, Xuanhe Pan,Feizhou Zhu,Congyuan Jiang,Qianqian Liu,Zhongyi Cheng,Gan Dai,Guojun Wu,Linqian Wang,Liyu Chen. Antibacterial activity and mechanism of silver nanoparticles against multidrug-resistantPseudomonas aeruginosa.International Journal of Nanomedicine, 2019 Feb 25;14:1469-1487.

7)Liu P, Li M, Guan X, Yu A, Xiao Q, Wang C, Hu Y, Zhu F, Yin H, Yi X, Liu L. J Kidney Cancer VHL. Clinical Syndromes and Genetic Screening Strategies of Pheochromocytoma and Paraganglioma.J Kidney Cancer VHL,2018, 5(4):14-22.

8)Minghao Li^#, Qianqian Liu^#, Peihua Liu, Xiaoping Yi, Xiao Guan, Anze Yu, Longfei Liu^*& Feizhou Zhu*.Long-term follow-up and novel splice donor mutation inMEN1in a Chinese family. Oncotarget, 2018, 9(2): 1577-1586.

9)Feizhou Zhu, Yong Peng, Lin Qi, Guoshu Bi, Yi He, Chunhao Jie, Ruomeng Yang, Ping An, Lu Yang, Jingjing Chen, Wenqin Xiao, Xi Zuo, Xiang Chen, Xiongbing Zu，Xiao Guan, Peihua Liu, Longfei Liu^*.Nested ARMS-qPCR is a fast and cost-saving method for single nucleotide polymorphism genotyping in clinical service.International Journal of Clinical and Experimental Medicine,2016, 9(8):16292-16300.

10)朱飞舟,陈利玉,陈汉春*. 16S rRNA基因序列分析法鉴定病原细菌.中南大学学报:医学版, 2013, 38(10): 1035-1041.

11)Weilong Liu, Lv Li, Md.Asaduzzaman Khan and Feizhou Zhu. Popular Molecular Markers in Bacteria.Molecular Genetics, Microbiology and Virology, 2012, 27(3): 103-107.

12)朱飞舟，陈利玉，刘新发，田奇，谈成，欧阳方丹，吴正理，陈汉春*. 10种常见细菌基因检测膜条的研制.微生物学杂志, 2011, 31(4):58-63.

13)ZHU Fei-Zhou, XIA Kun*.Functions of LRRK2 in Parkinson’s Disease.Progress in Biochemistry and Biophysics, 2010, 37(10): 1059-1066.

14)LIU Xiao-Ping^#, ZHU Fei-Zhou^#, WANG Guo, DENG Qi-Pan, ZHANG Jing, LI Qiong, LING Jie, WU Ling-Qian, LIANG De-Sheng, PAN Qian, LONG Zhi-Gao, GONG Hui-Yong, XIA Jia-Hui, ZHANG Zhuo-Hua, XIA Kun*. Role of PITX2 R62H Mutation inRing Dermoid of Cornea. Progress in Biochemistry and Biophysics,2008, 35(3): 274~282.

15)WANG Guo, LIU Xiaoping, PAN Qian, LIANG Desheng, WU Qianling, DAI Heping, ZHU Feizhou, XIA Kun* & XIA Jiahui.Functional analysis of three genetic disorders related PITX2 mutants.Chinese Science Bulletin,2006,51(2): 164-169.

教学论文

1)朱飞舟，何海伦，邓梅春.生物化学智慧教学.教育教学论坛, 2021年7月接受，2022年04月发表.

2)朱飞舟，汤立军，李文凯，何海伦，陈淑华.留学生高级生物化学全英文教学的探讨, 2021年6月接受，2021年11月发表.

3)陈淑华，李善妮，马昌杯，朱飞舟，张文，殷渊. Origin软件在福林-酚试剂法测定蛋白含量实验数据处理中的应用.教育教学论坛，2019, 51: 267-268.

4)朱飞舟，曾卫民，唐建华，宋元达，李文凯，龙苏，刘灿华，陈汉春*.对医学生开展生物化学双语教学的探究.山西医科大学学报：基础医学教育版, 2010，12（1）:85-87.

专著

1）张嵘，朱飞舟主编.《生物化学与分子生物学实验》第三版,北京：中国医药科技出版社，2020年11月.

2）陈汉春，陈淑华，邓梅春，付俊江，何海伦，李文凯，刘灿华，龙苏，骆亚萍，马昌杯，唐建华，杨盛清，叶湘漓，袁仕善，曾卫民，钟慧，朱飞舟.《生物化学与分子生物学实验教程》，科学出版社，2013年1月.