陈淑华，女，博士，教授，硕士生导师，中南大学生命科学学院生物化学与分子生物学系副主任。

2012年获得中南大学病理生理学博士学位，2013年至2015年在美国匹兹堡大学医学院开展博士后研究。主持国家自然科学基金2项、湖南省重点研发计划项目子课题2项和其他省级项目2项，参与国家和省级自然科学基金项目多项。在Journal of Leukocyte Biology、J Cell Mol Med、Front Immunol、Int J Mol Med等期刊发表SCI论文20余篇。获湖南省第九届自然科学二等（排第3）和第十五届自然科学二等优秀学术论文（排第1）。主编教材和参考书2部，参编教材和参考书3部；主持省级教改课题1项和校级教改课题3项；以第一或通讯作者发表教改论文5篇；指导大学生国家级竞赛三等奖2项。获校教学质量优秀奖3次、校级实验技术成果三等奖1次（排名第1），校级课程思政教学竞赛优秀奖1次等。

主要研究方向：1）血管与代谢性疾病发生机制；2）炎症与免疫。

代表性论文：

1.Chen Y, Zou H, Lu H, Xiang H,Chen S*. Research progress of endothelial-mesenchymal transition in diabetic kidney disease. J Cell Mol Med. 2022 Jun;26(12):3313-3322.

2.Liu Y, Xiang H, Xiong W, Ouyang J, Liu H, Zhao S, Xiao J , Li J, Shu Z, Wang X, Liu H, Zhang J, Fan J, Li Y,Chen S*and Lu H*. Glucolipotoxicity induces endothelial cell dysfunction by activating autophagy and inhibiting autophagic flow. Diab Vasc Dis Res. 2022 May-Jun;19(3):14791641221102513.

3.Wang X, Liang Z, Xiang H, Li Y,Chen S*and Lu H*. LKB1 Regulates Vascular Macrophage Functions in Atherosclerosis. Front Pharmacol. 2021 Dec 15;12:810224.

4.Liu H, Xiang H, Zhao S, Sang H, Lv F, Chen R, Shu Z, Chen AF,Chen S*, Lu H*. Vildagliptin improves high glucose-induced endothelial mitochondrial dysfunction via inhibiting mitochondrial fission. J Cell Mol Med. 2019,23(2):798-810.

5.Chen W, Xiang H, Chen R, Yang J, Yang X, Zhou J, Liu H, Zhao S, Xiao J, Chen P, Chen AF,Chen S* and Lu H*. S1PR2 antagonist ameliorate high glucose-induced fission and dysfunction of mitochondria in HRGECs via regulating ROCK1. BMC Nephrology. 2019, 20:135-143.

6.Chen P, Liu H, Xiang H, Zhou J, Zeng Z, Chen R, Zhao S, Xiao J, Shu Z,Chen S* and Lu H*. Palmitic acid-induced autophagy increases reactive oxygen species via the Ca²⁺/PKCα/NOX4 pathway and impairs endothelial function in human umbilical vein endothelial cells. Experimental and therapeutic Medicine. 2019, 17: 2425-2432.

7.Liu H, Peng H, Xiang H, Guo L, Chen R, Zhao S, Chen W, Chen P, Lu H*,Chen S*. TWEAK/Fn14 promotes oxidative stress through AMPK/PGC‑1α/MnSOD signaling pathway in endothelial cells. Mol Med Rep. 2018 Jan;17(1):1998-2004.

8.Chen S, Hoffman RA, Scott M, Manson J, Loughran P, Ramadan M, Demetris AJ, Billiar TR. NK1.1+ cells promote sustained tissue injury and inflammation after trauma with hemorrhagic shock. J Leukoc Biol. 2017 July, 102(1):127-134.

9.Chen S, Yang J, Xiang H, Chen W, Zhong H, Yang G, Fang T, Deng H, Yuan H, Chen AF, Lu H. Role of sphingosine-1-phosphate receptor 1 and sphingosine-1-phosphate receptor 2 in hyperglycemia-induced endothelial cell dysfunction. Int J Mol Med. 2015 Apr, 35(4): 1103-1108.

10.Chen S, Zuo, X, Yang, M , Lu, H , Wang N , Wang K, Tu Z , Chen, G, Liu M , Liu K, Xiao X. Severe multiple organ injury in HSF1 knockout mice induced by lipopolysaccharide is associated with an increase in neutrophil infiltration and surface expression of adhesion molecules. J Leukoc Biol. 2012,92 (4):851-857.