教育经历

2013.9-2017.7中国科学院大学/华东理工大学，理学博士

2010.9-2013.7东北师范大学，理学硕士

2006.9-2010.7东北师范大学，理学学士

工作经历

2017.7-2019.12华南理工大学，博士后

2020.6-2023.9中南大学，讲师

2023.9-至今中南大学，副教授

研究方向

探索表观遗传修饰因子在肿瘤发生和恶性进展过程中的潜在作用机理，并发掘精准治疗药物，为肿瘤的临床治疗提供理论依据和治疗新思路。主持国家自然科学基金青年项目1项、省级项目2项，获得湖南省“荷尖”人才称号，以第一或通讯作者身份在PNAS、AdvancedScience、Cancer Research等杂志上发表研究性论文。

代表性论文

(1)Hao Jiang#, Yang Wang#, Doudou Wen, Rongji Yu, Sayed S Esa, Kefeng Lv, Qing Feng, Jing Liu, Faxiang Li, Lan He*, Xiaotang Di*, Shubing Zhang*. Targeting C21orf58 is a Novel Treatment Strategy of Hepatocellular Carcinoma by Disrupting the Formation of JAK2/C21orf58/STAT3 Complex. Advanced Science, 2024, 11:e2306623.

(2)Shuanghui Liu#, Fanggui Shao#, Yourong Wang#, Yurui Zhang, Hongjia Yu, Ningxin Zhang, Lan He, Qingran Kong*, Hao Jiang*, Zhixiong Dong*. COX6C expression driven by copy amplification of 8q22.2 regulates cell proliferation via mediation of mitosis by ROS-AMPK signaling in lung adenocarcinoma. Cell Death Disease, 2024, 15(1):74.

(3)Shubing Zhang#, Jinhua Yan#, Lan He, Zhiping Jiang*, Hao Jiang*. STAT5a and SH2B3 novel mutations display malignancy roles in a triple-negative primary myelofibrosis patient. Cancer Gene Therapy, 2023, doi: 10.1038/s41417-023-00719-7.

(4)Qiao Xu, Lan He, Shubing Zhang, Xiaotang Di*, Hao Jiang*. Deubiquitinase OTUD3: a double-edged sword in immunity and disease. Frontiers in Cell and Developmental Biology, 2023, 11:1237530.

(5)Hao Jiang#, Yilang He#, Jia Zhao#, Ruimin Chang, Hailun He, Tan Li, Xingyu Zhang, Bo Shu, Wenxuan Zhang, Huaiyu Wang, Jing Liu, Shubing Zhang*, Yuetao Zhao*. Immunostimulant nanomodulator boosts antitumor immune response in triple negative breast cancer by synergism of vessel normalization and photothermal therapy. Nano Research, 2023, 16(8): 11149-11163.

(6)Dehua Hu, Yufeng Cai, Lan He, Hao Jiang*. Identification of a CircRNA-miRNA-mRNA Network and Integrated Analysis of Immune Infiltration in Oral Squamous Cell Carcinoma. Journal of Cancer, 2023,14(2):250-261.

(7)Samson Mugisha, Xiaotang Di, Cyrollah Disoma, Hao Jiang*, Shubing Zhang*. Fringe family genes and their modulation of Notch signaling in cancer. Biochim Biophys Acta Rev Cancer, 2022, 1877(4):188746.

(8)Samson Mugisha, Xiaotang Di, Doudou Wen, Yuetao Zhao, Xusheng Wu, Shubing Zhang, Hao Jiang*. Upregulated GATA3/miR205-5p Axis Inhibits MFNG Transcription and Reduces the Malignancy of Triple-Negative Breast Cancer. Cancers (Basel), 2022, 14(13):3057.

(9)Hao Jiang, Hui-Jun Cao, Ning Ma, Wen-Dai Bao, Jing-Jing Wang, Tian-Wei Chen, Er-Bin Zhang, Yan-Mei Yuan, Qian-Zhi Ni, Feng-Kun Zhang, Xu-Fen Ding, Qian-Wen Zheng, Yi-Kang Wang, MinZhu, Xiang Wang, Jing Feng, Xue-Li Zhang, Shu-Qun Cheng, Dan-Jun Ma, Lin Qiu, Jing-Jing Li*, Dong Xie*. Chromatin remodeling factor ARID2 suppresses hepatocellular carcinoma metastasis via DNMT1-Snail axis. PNAS, 2020, 117(9):4770-4780.